The Florida Highway Patrol is investigating an accident on State Road 417 that shut down several southbound lanes.
Orange County firefighters arrived at mile marker 34, between University Boulevard and Colonial Drive to see a minivan that rolled over.
Firefighters said at least nine people were injured, most with non-life threatening injuries.
Firefighters said one of those patients was a 10-year-old child with head injuries.
She was taken to Arnold Palmer Hospital with the most serious injuries.
At this time, officials said all lanes have reopened.
Watch Local 6 News and stay with ClickOrlando.com for updates on this story.